University of Bonn mathematicians and physicians have developed a new model for immunotherapy of cancer. The method could help to develop new treatment strategies and to understand why some approaches do not work with certain tumours.
One of the greatest problems in the fight against cancer is the great hardiness of the tumours, says the study published by technical journal 'Scientific Reports'.
Drug therapy often leads to initial success, which is then wiped out by a relapse. Sometimes the therapy has no affect at all against some cancer cells. Other cells develop resistance over the course of therapy.
Certain cells of the immune system, the so-called T-cells, can fight malignant tumours. Such cells are used or activated in a targeted manner to treat cancers.
The research groups of Prof. Dr. Thomas Tuting and Prof. Dr. Michael Holzel or the University of Bonn have demonstrated in their experiments on skin cancer that tumour cells can change their external appearance, if an inflammatory reaction occurs in the course of treatment.
Consequently, the T-cells no longer recognize them as harmful, and the cancer can continue to spread unimpeded.
A new model from mathematicians and physicians from the Excellence Cluster of the Hausdorff Center for Mathematics and ImmunoSensation of the University of Bonn now describes this effect mathematically, thus making it possible to analyse it.
In the future, the model could be used, among other things, for computer simulation of various therapeutic approaches and thus for the development of optimal treatment strategies.
GMT 13:44 2017 Tuesday ,25 April
Civic engagement at core of new partnership agreement between AUB and CIHGMT 03:46 2017 Sunday ,16 April
6 Delhi University colleges among India's top 10 in ministry's rankingGMT 19:47 2017 Saturday ,15 April
AUB opens third annual international sports tournamentGMT 12:01 2017 Wednesday ,12 April
Civic engagement at core of new partnership agreement between AUB and CIHGMT 07:41 2017 Wednesday ,12 April
Symposium at AUB addresses women's political participation in LebanonGMT 12:59 2017 Saturday ,08 April
Civic engagement at core of new partnership agreement between AUB and CIHGMT 09:17 2017 Saturday ,08 April
AUB President Fadlo Khuri Plants a Tree to Reaffirm AUB's Stance on Nature ConservationGMT 08:33 2017 Saturday ,08 April
AUB: KIP Conference a Forum for Diverse Voices Tackling Big IssuesMaintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©
Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©
Send your comments
Your comment as a visitor